Brian J. Larkin, MD

Brian J. Larkin

Orthopedic Surgeon - Joint Replacement & Reconstruction

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4.9
Based on 476 reviews.
Joint Replacement Surgery of Hip & Knee, Adolescent & Young Adult Hip Surgery
Fax: 303-321-8814
Brian J. Larkin

Brian J. Larkin, MD, a board-certified orthopedic surgeon, is a native of Michigan and joined Orthopedic Associates in 2012. Orthopedic Associates was one of the founding divisions of Orthopedic Centers of Colorado, a multi-site Orthopedic Group throughout the front range of Colorado founded in 2017.

His clinical expertise is in primary and revision hip and knee replacement and treatment of the young adult hip, including hip arthroscopy and open hip preservation surgery. He utilizes the latest developments in joint replacement surgery including anterior approach total hip arthroplasty, partial knee replacement, and minimally invasive knee and hip replacement. Dr. Larkin routinely performs many of his joint replacements in the outpatient setting, allowing patients to go home hours after surgery.

Dr. Larkin attended Yale University where he played varsity soccer and graduated with honors in biomedical engineering. He then obtained his medical degree at Wayne State University School of Medicine and completed his orthopedic surgery internship and residency at Henry Ford Hospital in Detroit, Michigan, serving as the Chief Resident in his final year. Dr. Larkin did his fellowship training in joint preservation, Resurfacing, and Replacement at Washington University in St. Louis, Missouri. He has been actively involved in research, including presentations at regional and national meetings, peer reviewed journal publications, and as an author of a book chapter.

Dr. Larkin is a Fellow of the American Academy of Orthopedic Surgeons and the American Association of Hip and Knee Surgeons, an Emerging Leader in the American Orthopedic Association, and active within the Colorado and Denver Medical Societies. Dr. Larkin serves as the Chief Medical Officer of Orthopedic Centers of Colorado and sits on the Medical Executive Board for Surgical Care Affiliates, helping craft policies and procedures for the region and the nation. Dr. Larkin chairs the High Acuity Sub-Committee for the SCA’s Medical Executive Board and recently completed Optum’s Sequoia Fellowship for healthcare leaders. He has also been the Co-Director of the Orthopedic Program at Rose Medical Center since 2016 and served as a consulting physician for the Colorado Avalanche from 2012-2017.

Education

  • Fellowship: Joint Preservation, Resurfacing, and Replacement, Washington University in St. Louis, St. Louis, MO
  • Residency: Orthopedic Surgery, Henry Ford Health System, Detroit, MI
  • Medical School: Wayne State University School of Medicine, M.D., Detroit, MI
  • Undergraduate School: Yale University, BS, New Haven, CT

Board Certifications

  • American Board of Orthopedic Surgery

Professional Sports Teams Affiliations

  • Colorado Avalanche, Consulting Physician 2012 – 2017

Memberships & Organizations

  • American Academy of Orthopedic Surgeons
  • American Association of Hip and Knee Surgeons
  • Colorado Medical Society
  • Denver Medical Society

Interests & Hobbies

  • Spending time with his wife and three children.
  • Soccer
  • Running
  • Tennis
  • Skiing
  • Golf

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Leadership & Outreach

Jennifer Speck, NP-C

Jennifer Speck, FNP-C

Board Certified Nurse Practitioner

Jennifer Speck FNP-C attended University of Colorado at Boulder and received a Bachelor of Science in Integrative Physiology. She then attended Denver College of Nursing and received her Bachelor of Science in Nursing. Jennifer is board certified through the American Academy of Nurse Practitioners specializing in Family Practice, and earned her Master’s of Science from Regis University in 2022. She is passionate about providing orthopedic care and connecting with each patient. She is excited to have joined such a reputable orthopedic team and help take care of hip and knee replacement patients. Learn more.

Dr. Larkin's Reviews

Tula G.
3 days ago
One word…amazing. I have arthritis in my hips…Dr. Larkin gave me a shot in both. My pain is gone! Thank you 🙏
Angela S.
3 days ago
Dr Larkin is awesome
Phil V.
4 days ago
Professional, courteous , fast , didn’t get the answers I wanted, but how often does that happen at the doctor’s office? Got answers I needed.
Dave V.
1 week ago
Had a great experience before, during and after my knee replacement. Highly recommend Dr Larkin and his team for being friendly, efficient and so good at what they do.
Jesse O.
1 week ago
Now that I have found Dr Larkin and his team, you couldn’t drag me to another team if my life depended on it. The level of concern, thoughtfulness, follow up, and care was unbelievable. And as I go through my recovery, I couldn’t ask for better partners! I highly recommend anyone needing Orthopedic support, to consider Dr. Brian Larkin and his team.
John P.
2 weeks ago
Dr Larkin and assistant did a great job explaining and giving me direction with my knee.
Kathy P.
2 weeks ago
Dr Larkin and his staff have always treated me with respect and dignity. Their medical expertise and ability to apply it to my needs helped me with the right medical treatment.
Joyce W.
3 weeks ago
Excellent!!
Douglas A.
3 weeks ago
Excellent care. I am very happy with my total knee replacement that was done by Dr Larkin.
Sandi Y.
1 month ago
Dr. Larkin was excellent ! He really spent time listening and discussing options with me. Most of all, he said he was going to be there for me in the future. First time a doctor has ever said that to me.
Andrew M.
1 month ago
Best ortho knee doctor in Denver
Susan F.
1 month ago
Dr Larsen was professional, helpful, and answered all my questions.
Marsha T.
1 month ago
Great doctor!
Iisa
1 month ago
I have had a knee replacement with Dr. Larkin and I was very pleased with the care of him and his team. Be prepared to wait for a while at his office though he’s a busy guy.
jeremy S.
2 months ago
Dr Larkin operated on my left hip this past Monday and I can’t say thank you enough, the man is amazing!!!!
Nancy H.
2 months ago
I have been a patient of Dr Larkin for years He is an excellent surgeon and an equally excellent person!. He is realistic, kind and has a great sense of humor. His staff are competent and helpful. I highly recommend Dr Larkin!
Bobbi C.
2 months ago
dr.Larkins has done both my knees and off has been so good eot work with! Thank you for the good care!
Theophilus G.
2 months ago
The team continue exceed expectation .
Michael S.
2 months ago
Dr Larkin seems to be doing a great job for the most part. He’s professional and does his best to answer my questions. He did my revision and is about to do a manipulation. Hopefully he can get this knee working better than the last doctor.
Holly F.
2 months ago
It is easy to make appointments and get information from the front desk staff. Staff are always friendly and helpful. I’ve had good experiences with Dr. Larkin as a surgeon. I like the fact that he is aware that physical therapy is an integral part of the total repair and healing process
Andy B.
2 months ago
This group is amazing! They knew week by week the level of my recovery. I was surprised how correctly they anticipated my progress and recovery.
Gwendolyn Y.
3 months ago
Thank you and your staff for the great service from the time of service until the end of my appointment.
Jack B.
3 months ago
My appointment was satisfactory in every aspect except that l waited over 45 minutes before I got to see the doctor.
Rich F.
3 months ago
I am 2 weeks and 3 days out from left hip replacement. My PT has me doing sled pushing, squats, one legged squats and step-ups. Joint pain is gone. Great surgeon...
Sara S.
3 months ago
I have been with Dr. Larkin for 6 years now. I found him in 2019, after 3 previous consultations with other surgeons, and I knew immediately I had found the right doctor!! He did my first hip replacement in 2020 and we have stayed in contact monitoring the progress of the other hip over the years. I just had my pre-op consult for my next hip replacement this week and I left that appointment feeling assured that it is time to proceed with the next one and firmly confident that I will receive the same incredible care and the same incredible outcome. Thank you for being amazing!!
Cynthia S.
3 months ago
I have been a patient of Dr Larkins for many years. When I have a knee issue, he is the doctor I seek medical assistance from. He is very knowledgeable in the field of orthopedics and always make you feel comfortable discussing your issue.
Eldon L.
3 months ago
Fan freaking tastic Doctor.. personable. Smart. Friendly. Numerous i would have him cut me again. I'm very grateful and happy with the outcome after my right knee replacement. I worked very hard from one week out after surgery to walking 3000-3500 steps every day from the second week out. I'm now walking on average a mile to a mile and a half every single day... My new right knee works like never has, they say I'll be jogging within 6 months. Wow. Great Job Dr. Larkin
Nancy Van B.
3 months ago
Very professional and very welcoming office. I appreciate that Dr. Larkin sits with me and clearly tells me what is happening next and spends time listening to me.
Grigoriy G.
3 months ago
Thank you for having a doctor like Larkin, he's a good doctor and has helped me many years.
Barbara B.
3 months ago
Dr. Larkin is my go-to surgeon for knees and hips. Always knows what to do for my issues. Personable too!
Terry W.
3 months ago
On time meeting, great communication from the PA, and helpful info on what's needed going forwars.
Rick S.
3 months ago
Dr. Larkin is one of the great ones.
Susan P.
3 months ago
Dr. Larkin has now been my surgeon for 2 knee replacements and has done a wonderful job! My care has been excellent both times, and the follow up from his office has been great!
Jon W.
4 months ago
Larkin is The Man! He and team were fabulous! Thank you.
Selena S.
4 months ago
Thank you Dr Larkin you are very good surgeon and a very kind person thank you for being my surgeon
Bonnie R.
4 months ago
My experience was excellent. I was particularly impressed that Dr. Larkin gave me the first injection at my intake appointment instead of making me come back. His pricing also seems very reasonable.
Dave B.
4 months ago
Dr Larkin & staff are highly skilled and personable too. They have replaced both of my knees.
Diane L.
4 months ago
Dr. Larkin replaced my left hip four years ago and I have not had any issues since. I had a lot of pain in my right hip recently, so I went back a couple of days ago and I will need surgery on my right hip, but not now. Dr. Larkin gave me a Cortizone shot and it’s already feeling better. I trust this practice and I trust my doctor.

Well, on August 12, 2025 Dr. Larkin did perform a complete right hip replacement and I am doing great. I love his team and the whole office is so helpful and professional. This is a well— oiled machine. I would recommend him every day all day! And I have two brand new hips to prove it!💯🎉

Dr. Larkin's Clinic Locations

Denver Rose/Cherry Creek Orthopedic Clinic

4700 E. Hale Pkwy, Ste 550
Denver
CO
80220

– ANNOUNCEMENT –
Effective 01/01/2026

United Healthcare HMO and HMO-POS plans require an authorized referral from your Primary care Provider (PCP).

We will honor existing appointments through 03/01/2026 without authorization. However, any planned or ongoing treatment may be delayed if authorization is not received (IE: MRI, Surgery, PT/OT).

Please contact your PCP as soon as possible to obtain an authorization if you wish to be seen today or to avoid delays in care.