Brian J. Larkin, MD

Orthopedic Surgeon - Joint Replacement & Reconstruction

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4.9
Based on 455 reviews.
Joint Replacement Surgery of Hip & Knee, Adolescent & Young Adult Hip Surgery
Fax: 303-321-8814
Brian J. Larkin

Brian J. Larkin, MD, a board-certified orthopedic surgeon, is a native of Michigan and joined Orthopedic Associates in 2012. Orthopedic Associates was one of the founding divisions of Orthopedic Centers of Colorado, a multi-site Orthopedic Group throughout the front range of Colorado founded in 2017.

His clinical expertise is in primary and revision hip and knee replacement and treatment of the young adult hip, including hip arthroscopy and open hip preservation surgery. He utilizes the latest developments in joint replacement surgery including anterior approach total hip arthroplasty, partial knee replacement, and minimally invasive knee and hip replacement. Dr. Larkin routinely performs many of his joint replacements in the outpatient setting, allowing patients to go home hours after surgery.

Dr. Larkin attended Yale University where he played varsity soccer and graduated with honors in biomedical engineering. He then obtained his medical degree at Wayne State University School of Medicine and completed his orthopedic surgery internship and residency at Henry Ford Hospital in Detroit, Michigan, serving as the Chief Resident in his final year. Dr. Larkin did his fellowship training in joint preservation, Resurfacing, and Replacement at Washington University in St. Louis, Missouri. He has been actively involved in research, including presentations at regional and national meetings, peer reviewed journal publications, and as an author of a book chapter.

Dr. Larkin is a Fellow of the American Academy of Orthopedic Surgeons and the American Association of Hip and Knee Surgeons, an Emerging Leader in the American Orthopedic Association, and active within the Colorado and Denver Medical Societies. Dr. Larkin serves as the Chief Medical Officer of Orthopedic Centers of Colorado and sits on the Medical Executive Board for Surgical Care Affiliates, helping craft policies and procedures for the region and the nation. Dr. Larkin chairs the High Acuity Sub-Committee for the SCA’s Medical Executive Board and recently completed Optum’s Sequoia Fellowship for healthcare leaders. He has also been the Co-Director of the Orthopedic Program at Rose Medical Center since 2016 and served as a consulting physician for the Colorado Avalanche from 2012-2017.

Education

  • Fellowship: Joint Preservation, Resurfacing, and Replacement, Washington University in St. Louis, St. Louis, MO
  • Residency: Orthopedic Surgery, Henry Ford Health System, Detroit, MI
  • Medical School: Wayne State University School of Medicine, M.D., Detroit, MI
  • Undergraduate School: Yale University, BS, New Haven, CT

Board Certifications

  • American Board of Orthopedic Surgery

Professional Sports Teams Affiliations

  • Colorado Avalanche, Consulting Physician 2012 – 2017

Memberships & Organizations

  • American Academy of Orthopedic Surgeons
  • American Association of Hip and Knee Surgeons
  • Colorado Medical Society
  • Denver Medical Society

Interests & Hobbies

  • Spending time with his wife and three children.
  • Soccer
  • Running
  • Tennis
  • Skiing
  • Golf

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Jennifer Speck, NP-C

Jennifer Speck, FNP-C

Board Certified Nurse Practitioner

Jennifer Speck FNP-C attended University of Colorado at Boulder and received a Bachelor of Science in Integrative Physiology. She then attended Denver College of Nursing and received her Bachelor of Science in Nursing. Jennifer is board certified through the American Academy of Nurse Practitioners specializing in Family Practice, and earned her Master’s of Science from Regis University in 2022. She is passionate about providing orthopedic care and connecting with each patient. She is excited to have joined such a reputable orthopedic team and help take care of hip and knee replacement patients. Learn more.

Dr. Larkin's Reviews

Sara S.
I have been with Dr. Larkin for 6 years now. I found him in 2019, after 3 previous consultations with other surgeons, and I knew immediately I had found the right doctor!! He did my first hip replacement in 2020 and we have stayed in contact monitoring the progress of the other hip over the years. I just had my pre-op consult for my next hip replacement this week and I left that appointment feeling assured that it is time to proceed with the next one and firmly confident that I will receive the same incredible care and the same incredible outcome. Thank you for being amazing!!
Cynthia S.
I have been a patient of Dr Larkins for many years. When I have a knee issue, he is the doctor I seek medical assistance from. He is very knowledgeable in the field of orthopedics and always make you feel comfortable discussing your issue.
Eldon L.
Fan freaking tastic Doctor.. personable. Smart. Friendly. Numerous i would have him cut me again. I'm very grateful and happy with the outcome after my right knee replacement. I worked very hard from one week out after surgery to walking 3000-3500 steps every day from the second week out. I'm now walking on average a mile to a mile and a half every single day... My new right knee works like never has, they say I'll be jogging within 6 months. Wow. Great Job Dr. Larkin
Nancy Van B.
Very professional and very welcoming office. I appreciate that Dr. Larkin sits with me and clearly tells me what is happening next and spends time listening to me.
Grigoriy G.
Thank you for having a doctor like Larkin, he's a good doctor and has helped me many years.
Barbara B.
Dr. Larkin is my go-to surgeon for knees and hips. Always knows what to do for my issues. Personable too!
Terry W.
On time meeting, great communication from the PA, and helpful info on what's needed going forwars.
Andy B.
This group is amazing! They knew week by week the level of my recovery. I was surprised how correctly they anticipated my progress and recovery.
Rick S.
Dr. Larkin is one of the great ones.
Susan P.
Dr. Larkin has now been my surgeon for 2 knee replacements and has done a wonderful job! My care has been excellent both times, and the follow up from his office has been great!
Jon W.
Larkin is The Man! He and team were fabulous! Thank you.
Selena S.
Thank you Dr Larkin you are very good surgeon and a very kind person thank you for being my surgeon
Bonnie R.
My experience was excellent. I was particularly impressed that Dr. Larkin gave me the first injection at my intake appointment instead of making me come back. His pricing also seems very reasonable.
Dave B.
Dr Larkin & staff are highly skilled and personable too. They have replaced both of my knees.
Diane L.
Dr. Larkin replaced my left hip four years ago and I have not had any issues since. I had a lot of pain in my right hip recently, so I went back a couple of days ago and I will need surgery on my right hip, but not now. Dr. Larkin gave me a Cortizone shot and it’s already feeling better. I trust this practice and I trust my doctor.

Well, on August 12, 2025 Dr. Larkin did perform a complete right hip replacement and I am doing great. I love his team and the whole office is so helpful and professional. This is a well— oiled machine. I would recommend him every day all day! And I have two brand new hips to prove it!💯🎉
MystieRaven F.
I was impressed with the entire staff at Dr. Larkins’s office. All were friendly, helpful, and knowledgeable. Dr. Larkin showed honest and accurate information for my Care. I highly recommend him and his staff!
John B.
Dr. Larkin is very knowledgeable and genuinely cares about patients, I am very fortunate to have him on my team. Thank you.
Rhonda P.
I was able to make an appointment within days of calling. Online registration was available and easy. Parking was easily available. I was taken back for my appointment on time and was seen by the PA, sent for an X-ray and met and visited with Dr Larkin. He explained the X-rays and questions were answered to my satisfaction. I was encouraged to call if I thought of any other questions. I was given paperwork and instructions and I was done. Was impressed with the efficiency and friendliness of the office staff.
Douglas W.
As always, Dr. Larkin and his staff addressed my concerns and questions. He discussed my future surgery in terms and words that I understood.
Another visit that I left with confidence in Dr. Larkin and his staff.
Joseph O.
Very knowledgeable and professional. High level of trust with their expertise.
Tula G.
One word…amazing. I have arthritis in my hips…Dr. Larkin gave me a shot in both. My pain is gone! Thank you 🙏
Elaine S.
Efficient and caring staff. Dr Larkin listened to my concerns, and after discussing his findings with me, shared his treatment plan. He is an excellent surgeon with superb technical skills. So pleased with his care.
Joe F.
My follow up consultation with Dr. Larkin was for a 20 year follow up for a hip replacement. Dr. Larkin was thorough in answering my questions. His focused history, physical exam and X-ray review guided his conclusion of the continued well-being of the hip prosthesis as well as the status of the other native hip. He quickly appreciated my athletic interests, and per my request offered his experiential advice for future healthy activities.

I also appreciate the review and explanation of the hip/pelvis X-Ray findings with Physician Assistant Rachelle, and her understanding that I am a physician myself and therefore going into detail of the radiographic images.

This 20 year follow up evaluation was most important to me, and it was clear to me that Dr. Larkin and Rachelle PA acknowledged my great interest in the findings of this encounter and their helpfulness in guiding me forward.
Mary O.
Caring and professional. Dr Larkin always takes time to answer questions and address concerns. The best!
Bob P.
Dr. Larkin preformed a knee replacement surgery on my right knee 13 months ago and we are getting ready to replace the other knee. I don’t think I would have anyone else perform this surgery but Dr. Larkin. He’s very easy to communicate with and he explains everything he will be doing. He’s very laid back, and a very nice person to boot.
Phil K.
Love, love, love Dr. Larkin at OCC. He did my Total Knee Replacement almost two years ago. His finishing work was so good that you can barely see a scar, his bedside manner is awesome, and working with everyone on his staff is a joy. If I could rate him a 6 on this scale of 1to 5, I would!
Bob C.
My exam was very thorough with time to answer all my questions & address my concerns. Between Dr. Larkin, PA Melissa, & Maggie the surgical scheduler, I feel confident with my decision to move forward.
Debbie O.
Dr Larkin and his staff were very attentive and worked to address my health issue with expediency.
Car “CarM” M.
My intake was fairly timely, the tech put me in a room and was going to order an x-ray before I saw the doctor. I sat there for an hour in the room and no one ever came. Not sure what happened with that. The doctor came in and there was some confusion as to why I hadn't had the X-ray. The doctor was fantastic answered all my questions gave me all the information I wanted. Not sure what happened with the staff? The doctor was great!
Kathleen M.
Dr Larkin and his team are the best. On time, attentive. Addressed every issue and very organized and through. I am fortunate to work with their team
Carol Q.
Our experience was over the top! We are from out of town and had no where to go. The staff squeezed my husband into Dr. Larkin’s very busy schedule. Each person who worked with Bill showed concern and compassion. We cannot thank everyone enough! Bill and Carol
Kathy P.
Dr Larkin and his staff have always treated me with respect and dignity. Their medical expertise and ability to apply it to my needs helped me with the right medical treatment.
Glenda V.
Dr. Larkin is an exceptional surgeon with incredible bedside manner!
Nancy B.
My husband's appointment was conducted promptly with kind professionalism. Dr. Larkin was clear with his observations and very thorough in looking at my husband's situation. We left with gratitude that we had been referred to an exceptionally fine doctor.
Susan C.
Dr Larkin & his staff are awesome. They listened to my concerns & made sure that I was taken good care of. Everyone is friendly, caring & so easy to deal communicate with.
Thank You
Lara B.
The best Dr! Thank you so much for taking such a good care of my mom and her knees. You are the best.
Phil C.
Dr. Larkin is cordial and clear in his communication, and his team is great. After the appointment, I have a good understanding of my options for treatment and an invitation to follow up when ready for the next step.
John P.
Dr Larkin and assistant did a great job explaining and giving me direction with my knee.
Robert K.
Dr. Larkin and his staff at Orthopedic Associates x-rayed and examined my injured hip. They reviewed the results with me thoroughly and provided exercises for rehabilitation. I found their help very informative.

Dr. Larkin's Clinic Locations

Denver Rose/Cherry Creek

4700 E. Hale Pkwy, Ste 550
Denver
CO
80220